DAY 1 - Thursday, Sep 20


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WELCOME: Alexander Eggermont

in partnership with SITC rgb 125
An application has been made to the UEMS EACCME for accreditation of this event

Session I: Immunology from the basics to the clinic
Moderators: A. Bobard-GRCC / E. Deutsch-GRCC

clock circular outline 8:30 - 9:00 am

1. Altered myelopoiesis in cancer
Vincenzo Bronte, University of Verona ico it

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2. Adaptive T cell immunity
Anna Mondino, San Raffaele Scientific Institute ico it

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3. State of the art clinical immunology: the melanoma revolution
Alexander Eggermont, GRCC, Villejuif ico fr

Session II: Immunotherapy from bench to bedside
Moderators: H. Fridman-CRC / E. Romano-Curie institute

coffee cup Coffee Break: 10:00-10:30 am

 clock circular outline 10:30 - 11:15 am Keynote IMMUNOLOGICAL CELL DEATH

4. Immunogenic cell death in cancer therapy
Guido Kroemer, CRC, Paris ico fr

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5. Autophagy in cancer therapy – A quality-quantity conundrum
Lorenzo Galluzzi, WCM, NY ico usa

clock circular outline 11:45 am - 12:15 noon

6. Immune contexture in the era of cancer immunotherapies
Jérome Galon, CRC, Paris ico fr

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7. Is there a role for radiation in the field of Intratumoral immunotherapy?
Aurélien Marabelle, GRCC,Villejuif ico fr

clock circular outline 12-45 - 2:00 pm cutleryLUNCH


Session I: Radiotherapy from basic concepts to immunomodulation
Moderators: S. Rivera-GRCC / P. Maingon-SFRO

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1. The basics of radiotherapy from precursors to carbon ions and molecular-targeted radiotherapy
Cyrus Chargari, GRCC, Villejuif ico fr

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2. Side effects of radiotherapy and immune treatment: How to mitigate them?
Dirk de Ruysscher, MAASTRO clinic, Maastricht, NLico nl

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3. What have we learned so far from phase 1 and 2 immunoRad-trials?
Piet Ost, UGhent ico.belgique

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4. The effects of radiotherapy on antigen processing and presentation
William Mc Bride, UCLA ico usa

coffee cup Coffee Break: 4:15-4:45 pm

Session II: Macrophages
Moderators: E. Solary-GRCC / M. Mondini-GRCC

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5. Macrophages reprogramming modulates the immune tumor microenvironment in mouse models of
HPV-driven cervical cancer
Enrico Giraudo, IRCC, Torino ico it

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6. What can we learn from the effects of irradiation of hematopoietic stem cells?
Paul-Henri Roméo, CEA, Fontenay aux Roses ico fr

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7. Macrophage reprogramming, DNA damage response and radiation therapy
Jean-Luc Perfettini, GRCC, Villejuif, ico fr

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cocktail poster Champaign poster session

DAY 2 - Friday, Sept 21


Session III: Innate sensors
Moderators: S. Postel-Vinay-GRCC / V. Soumelis-Curie institute

 clock circular outline 8:30 - 9:00 am

8. DNA damage sensing and innate immunity converge to regulate tumor-host interactions
Sandra Demaria, WCM, NY ico usa

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9. Pattern Recognition Receptor and Interferon Signaling in Cancer and Cancer Immunotherapy
Andy Minn, UPenn, Philadelphia ico usa

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10. Pre-clinical and clinical data for combining immunotherapy plus radiation as systemic therapy
James Welsh, MDACC, Houston ico usa

coffee cup Coffee Break: 10:00 - 10:30 am

Session IV: Tumor immune microenvironment
Moderators: C. Badoual-HEGP / S. Depil-Cellectis

clock circular outline 10:30 - 11:15 am
Keynote T CELLS

11.Orchestration of Immune Attack Against Tumors : Lessons From Ovarian Cancer
George Coukos, CHUV, Lausanne ico Sui

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12. Altering the microenvironment for improving radio-immunotherapy
Tim Illidge, Manchester University ico uk

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13. Co-stimulation, co-inhibition and cross-priming at the crossroad of radio-immunotherapy
Ignacio Melero, CIMA, Pampelona ico sp

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14. Clinical Translation of Radio-Immunotherapy Combinations
Fernanda Herrera, CHUV, Lausanne ico Sui

clock circular outline 12-45 - 2:00 pm cutleryLUNCH

Session V: Abscopal effect
Moderators: S. Demaria-WCM / S. Dovedi-Medimmune

clock circular outline 2:00 - 2:45 pm Keynote OLIGOMETASTASIS

15. Oligometastasis and the immune contexture, how much do we have to treat??
Ralf Weichselbaum, Chicago University ico usa

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16. Barriers to the abscopal effect of radiotherapy
Silvia Formenti, WCM, NY ico usa

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17. TCR clonal dynamics in mice and patients treated with radiotherapy and immune checkpoint blockade
Nils Rudqvist, WCM, NY ico usa

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18. Combining radiotherapy with checkpoint inhibitors and TGFb inhibitors
David Raben, UColorado ico usa

coffee cup Coffee Break: 4:15 - 4:45 pm

Session VI: Radiomics
Moderators: N. Paragios-Centrale Supélec / C. Robert-GRCC

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19. Pseudo-progression: myth or reality?
Caroline Caramella, GRCC, Villejuif ico fr

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20. Cancer Precision Medicine & Artificial intelligence: Past, Present & Future
Nikos Paragios, Centrale-Supélec  ico fr

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21. Functional imaging to optimize the outcome of immunotherapy ?
Eric Deutsch, GRCC, Villejuif ico fr

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22. Radiomics and immunocytokines
Philippe Lambin, Maastricht University ico nl


wine glassesGala dinner

DAY 3 - Saturday, Sept 22


Session VII: Virus and Microbes
Moderators: T. Naas CHU Bicêtre / A. Bigorgne GRCC

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22. Modulating immune responses to radiation and viral therapies.
Kevin Harrington, ICR, London ico uk

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23. Radiotherapy/Immunotherapy combinations - the translational opportunities.
Alan Melcher, ICR, London  ico uk

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24. Microbiome and cancer
Laurence Zitvogel, GRCC, Villejuif ico fr

ico nl

coffee cup Coffee break 10:45-11:15 am

Session VIII: Biomarkers
Moderators: D. Raben-UColorado / S. Michiels-GRCC

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25.Mathematical Modeling of Cancer Immunotherapy and Its Synergy with Radiotherapy
Raphael Serre, Aix-Marseille University ico fr

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26. The histopathological  effects of chemoradiotherapy on regional lymph nodes in oesophageal cancer
Heike Grabsch, Maastricht University ico nl

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27. Germ-line microRNA biomarkers of radiation and immune toxicity
Johann B. Weidhaas, UCLA ico usa

clock circular outline 12:45-1:00 pm

Concluding remarks, Eric Deutsch

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